Stuckey predicted that Isaiah Likely will score a touchdown against the Buffalo Bills, offering value at 4-to-1 odds. He noted that the Bills have shown vulnerabilities in the red zone and against tight ends, which Likely could exploit. With the Ravens potentially needing to pass more, Likely is expected to have an increased role and favorable matchups in the middle of the field. Stuckey highlighted that Likely came close to scoring in the previous game and believes he is poised to find the end zone in this matchup.

Chris Raybon recommended betting on Isaiah Likely to score a touchdown at 4 to 1 odds against the Bills. He expects Likely to find the end zone due to a great matchup and potential Bills red zone regression.

Stuckey predicted that Isaiah Likely would exceed 33.5 receiving yards against the Bills. He believes Zay Flowers will not play or won't be effective, leading to more targets for Likely, who will benefit from favorable matchups against vulnerable Bills linebackers and safeties.

Adam Levitan highlighted that with Zay Flowers out, Isaiah Likely set a season high with 28 snaps lined up out wide and ran 19 routes, becoming the biggest beneficiary of Flowers' absence. Levitan suggests that Likely's increased usage makes him a strong fantasy option, especially considering doubts about Flowers' availability for the upcoming game against the Bills.